Connecting multiple office sites or datacenters securely and efficiently is a critical challenge for modern businesses. Traditional VPN solutions like IPsec or OpenVPN can be complex to configure and maintain, especially in multi-site environments. WireGuard offers a lightweight, fast alternative that's easier to set up. VyOS 1.5 fully supports WireGuard, making it an excellent choice for organizations looking to interconnect multiple datacenters or sites. In this guide, we'll show you how to set up a site-to-site WireGuard tunnel on VyOS 1.5. We'll cover routing, firewall configuration, and best practices. By the end, your sites will be securely connected over the internet with traffic routed effectively between LANs.

WireGuard is the protocol all three products are built on, so "WireGuard vs Tailscale" is the wrong framing. The real question is who runs your control plane: Tailscale's SaaS, a self-hosted Headscale, NetBird's fully open stack, or nobody (raw WireGuard). This guide draws the protocol-vs-control-plane-vs-relay map cleanly, compares the four on the dimensions you actually decide on, explains why kernel and userspace WireGuard perform differently, and gives an infrastructure operator's verdict, including the angle the vendor-written SERP ignores: mesh access into management and out-of-band networks.